Original Research Article

EFFECTIVENESS OF STRUCTURED TEACHING PROGRAM ON KNOWLEDGE REGARDING PREDIABETES AND ITS PREVENTION

R. PRITI, M. SEELI

Asian Journal of Advances in Medical Science, Volume 4, Issue 3, Page 1-4

Background: Prediabetes is a state in which blood glucose levels are higher than normal, but lower than those required for a diagnosis of diabetes. Adults with prediabetes are at a high risk of developing type 2diabetes and its associated complications. The prevalence of prediabetes and type 2diabetes is increasing worldwide and exhibits a challenge on the health care system. It is estimated that worldwide 6.7% of the adult population have prediabetes, half of them aged less than 50years old, about one third are aged between 20-39years old. The aim of present study is to evaluate the effectiveness of structured teaching program on knowledge regarding prediabetes and its prevention among degree student.

Methods: A quantitative pre experimental method was use for this study. The sample consists of 60degree students of selected colleges, Bangalore. They were chosen by a purposive sampling technique. One group pre test- post test design was used to collect the data from subjects.

Results: In the pretest, majority of the subjects had inadequate knowledge with a mean knowledge score of 36.8% whereas in post test there was a significant gain in mean knowledge score of 67.6%.A significant association was found between socio demographic variables. χ 2 value  was 78.367 at 0.05 level of significance.

Conclusion: The finding of the study shows that in the pretest, majority of the degree students had inadequate knowledge regarding prediabetes and its prevention, where as in posttest majority of students had gained adequate knowledge after administration of structured teaching program. Thus, the study findings indicate that structured teaching program was effective in enhancing the knowledge regarding prediabetes and its prevention among degree students in selected colleges, Bangalore.

Original Research Article

TO DETERMINE THE EFFICACY OF 0.12%CHLORHEXIDINE MOUTHRINSES IN REDUCING VIABLE BACTERIAL COUNT IN DENTAL AEROSOLS WHEN USED AS A PREPROCEDURAL RINSE DURING THE PANDEMIC ERA -A PROSPECTIVE CLINICAL PILOT STUDY

V. RAMYA, SURENDRANATH ., MOHAN VALIATHAN, SAJID HUSSAIN

Asian Journal of Advances in Medical Science, Volume 4, Issue 3, Page 17-24

Background: In dentistry , aerosols being the major concerns that brings about transmission of infectious agents and harmful to patients and dentists . Thus the vigilant use of barriers, appropriate immunisation procedures all could safeguard the dental fraternity from the ill effects of aerosols.

Aim: To Determine The Efficacy of 0.12% chlorhexidine mouth rinse as preprocedural rinse in reduction of bacterial aerosol contamination generated during Ultrasonic scaling in a closed operatory and compared with1% Povidone iodine rinse and without preprocedural rinse.

Materials and Methods: Thirty patients were selected from Department of Periodontics, Sree Balaji Dental College and Hospital, Chennai. The subjects were grouped into A -10 patients each receive 1% POVIDINE IODINE mouth rinse and Group B of 10 patients received 0.12% CHLORHEXIDINE mouth rinse respectively as a pre-procedural rinse. Group C 10 patients without preprocedural rinse. The aerosols produced by the ultrasonic unit were collected on blood agar plates placed at 8 standard positions around the dental chair. These plates were sent for microbiologic analysis for the assessment of bacterial Colony Forming Units (CFUs) was evaluated and statistically analysed.

Results: The significance of the study was both the mouthrinses reduced the bacterial colony forming units (CFUs) in aerosol samples. 0.12%Chlorhexidine mouth rinses were found to be superior to 1%Povidone iodine in reducing aerosolized bacteria when used preprocedurally.

Conclusion: The study highlights the efficacy of preprocedural mouth rinses , during any dental treatment which generates aerosols, reduces the risk of cross- contamination within the dental operatory.

Original Research Article

EFFECTIVENESS OF SELF INSTRUCTIONAL MODULE ON KNOWLEDGE REGARDING FACTORS AFFECTING NORMAL FETAL GROWTH AND DEVELOPMENT AMONG ELIGIBLE COUPLES

JENIL NEUPANE, PRITI RAWAT, DEEPTI SHARMA

Asian Journal of Advances in Medical Science, Volume 4, Issue 3, Page 25-29

Background: Prenatal development includes the development of the embryo and of the fetus during a viviparous animal's gestation. It starts with fertilization, in the germinal stage of embryonic development and continuous in fetal development until birth. The factors which affecting normal fetal growth and development can be due to maternal, placental or fetal. Maternal factors include maternal size, weight, height, nutritional state, anemia, smoking, substance abuse, noise exposer etc. Placental factors include size, microstructure, umbilical blood flow, transporters and binding proteins, nutrient utilization and nutrient production and Fetal factors include the fetus genome, nutrient production, and hormone output. Inappropriate growth and development lead to low birth weight, fetal death.

Objectives: The aim of the study to assess the effectiveness of SIM regarding factors affecting normal fetal growth and development among eligible couples in selected rural community of Bangalore.

Design: A pre experimental one group pre-test posttest design was used for the study.

Subjects: The sample consists of 60 eligible couples in selected rural community of Bangalore.

Methods: A nonprobability purposive sampling technique was used to select the sample for the study.

Results: In the pre-test the sample had inadequate knowledge with the mean of 43.3% and standard deviation of 14.8 % where as in the post test there was significant gain in mean knowledge score of about 87.3% with the standard deviation of 10.1%.

Conclusion:. In the pretest majority of the respondents had inadequate knowledge Whereas in the posttest majority of the respondents had adequate knowledge. Thus the study indicates that he SIM was effective in enhancing the knowledge regarding factors affecting normal fetal growth and development.

Original Research Article

AUTOMATED ASSAY OF Caenorhabditis elegans WILD-TYPE AND CYSTATIN MUTANTS THRASHING BEHAVIOUR IN THE PRESENCE OR ABSENCE OF PLANT DERIVED CYSTEINE PROTEINASES (CPs)

VICTOR S. NJOM

Asian Journal of Advances in Medical Science, Volume 4, Issue 3, Page 30-37

The intensive use and over dependence on synthetic anthelmintics for the treatment of nematode infection on only a few drugs with similar mode of action has put pressure on such drug candidates with resultant loss of potency due to development of resistance by target nematodes. Plant materials with promising quality and efficacy to substitute for current anthelmintics include the plant derived cysteine proteinases (CPs). Motility is an important indication of the effectivenes of a drug and is a characteristic of  phenotype useful for high thoroughput screening of chemical and theraputic agents. This study determined the effect of cysteine proteinases on motility of C. elegans strains (wild type and cystatin null mutants) using the worm watcher device. Results show that motility of C. elegans was affected differently in PLS or papain. The effect of CP on motility of C. elegans strains was dependent on CP type, time of incubation and concentration of CP. Generally there was no significant difference (P>0.05) between mean motility of WT, cpi-1 and cpi-2 null mutant C. elegans in PLS when compared with PLS+E64 (control). There was a statistically significant (P ˂0.05) effect of papain dose on all the strains. Enzyme specificity on cuticle structural proteins might be responsible for difference in pattern of attack observed between papain and PLS. CP has potency for use as effective anthelminthic.

Review Article

THE NEUROPROTECTIVE EFFECTS OF MEDICINAL PLANTS ON ALZHEIMER`S DISEASE: A REVIEW

S. PRAJWAL, M. RUPESH KUMAR

Asian Journal of Advances in Medical Science, Volume 4, Issue 3, Page 5-16

In the 21st century, the human population is suffering from a neurodegenerative disorder in which neuronal death occurs due to a long-term chronic condition causing substantial major health concerns. When neurons die, they are not regenerated, causing cognitive impairment, i.e., Alzheimer’s disease, Parkinson’s disease, schizophrenia, and dementia. This review concentrates only on Alzheimer’s disease aetiology and various plants having potent neuroprotective activity related to Alzheimer’s disease. The most common aetiology of Alzheimer’s disease is a deposition of APP protein, hyperphosphorylation of Tau protein, a reduction in acetylcholine and oxidative stress, which are discussed briefly. Moreover, pertinent evidence is also discussed for medicinal plants with potent or promising neuroprotective activity related to Alzheimer’s disease.

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