PROTECTIVE EFFICACY OF Moringa oleifera AGAINST RADIATION AND MERCURIC CHLORIDE INDUCED HAEMATOLOGICAL CHANGES IN MICE
MURALIDHAR PANCHARIYA
Department of Zoology, Radiation Biology Laboratory, Govt. Dungar College, Bikaner (Raj), India.
POOJA RANI KHATRI
Department of Zoology, Radiation Biology Laboratory, Govt. Dungar College, Bikaner (Raj), India.
R. K. PUROHIT *
Department of Zoology, Radiation Biology Laboratory, Govt. Dungar College, Bikaner (Raj), India.
MANISHA AGARWAL
Department of Zoology, Radiation Biology Laboratory, Govt. Dungar College, Bikaner (Raj), India.
ARUNA CHAKRAWARTI
Department of Zoology, Radiation Biology Laboratory, Govt. Dungar College, Bikaner (Raj), India.
DEEPAK MITTAL
Department of Zoology, SSSUTMS, Sehore (M.P.), India.
*Author to whom correspondence should be addressed.
Abstract
The present study was planned to investigate the impact of the Moringa oleifera against combined administration of mercuric chloride and radiation on haematogical changes in mice. The mice were exposed to mercuric chloride (0.5 ppm) and gamma radiation (2.0Gy) simultaneously and individually. The experimental groups were given Moringa oleifera seven days prior to radiation or mercuric chloride treatment. The changes included increase or decreae in the various heamatological parameters viz. RBC, WBC, Hb, MCH, MCHC etc. In the combined treatment groups the changes were more severe showing synergistic effect. An early and fast recovery in Moringa pre-treated groups may be due to the protection provided by the drug.
Keywords: Radiation, mercuric chloride, Moringa oleifera, mice.